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What is MetaboTip?

Metabognostics introduces a new sweat sampling device – MetaboTip – for human
biomonitoring to empower healthcare providers and practitioners in diagnosing complex diseases in an individualized approach.

Sweat Analysis:

Sweat is a surprisingly rich source for determining metabolic parameters and emerges as an ideal biofluid for diagnosis. Sweat is constantly secreted by dedicated glands on the skin surface all over the body. However, these glands are particularly frequent on the palms of the hand and the fingertips. The sweat composition is highly dynamic and responsive to physiological/pathological processes.


Sweat Sampling

Sweat collection is completely non-invasive and simple. In contrast to blood-based tests, Metabotip does not require professional personnel. Minute amounts of sweat from the fingertip are sufficient for accurate and precise determination of metabolic parameters.

How does it work?

Simple, Quick, and Completely Non-Invasive:

Here’s how:

1. Prepare for Sampling: Wash your hands with lukewarm water (Do not use soap!)
and gently dry them with a one-way paper towel. Wait for one minute.

2. Collect Your Sample:
– Remove the sampling unit from the container.
– Place it between the tips of your thumb and index finger.
– Apply pressure for one minute, squeezing the unit about 10 times.
– Return the sampling unit to the container and securely close the lid.

3. Storing Your Sample:
– Keep it at room temperature for up to 1 day.
– Store at 4°C for up to a week.
– Freeze at -20°C for longer storage.

4. Deliver Your Sample to MetaboGnostics:

No cooling is needed during transport.

Wash hands with luke warm water without (!) soap

Gently dry hands with a paper towel.

Wait for one minute – do not touch anything during this time.

Remove the sampling unit from the container.

Place sampling unit between the lips of your thumb and index finger. Children can use their thumb, index finger or middle finger. Apply pressure for one minute, squezing the unit about 10 times.

Return the sampling unit to the container and securely close the lid.

Benefits of Metabotip:

  • Low cost
  • Metabotip delivers an extensive range of molecular information at a fraction of the
    costs compared to other techniques.
  • Non-Invasive
  • The sampling procedure is completely non-invasive, eliminating risks and
    discomfort during sample collection. No specialized medical or paramedical
    personnel is required.
  • Individual Metabolic Parameters
  • Metabotip collects metabolic parameters of individuals and allows for personalized
    diagnostics.
  • Convenient Sampling
  • Sweat collection from fingertips is simple, fast and does not require specialized
    training.
  • No Sweat Stimulation
  • Unlike methods that require induced sweating, Metabotip analyzes natural,
    unstimulated sweat, thereby avoiding potential biases.
  • Comprehensive Profiling
  • Unlike methods that focus on a few pre-selected metabolites, Metabotip provides a
    holistic view by detecting over 600 metabolites in a single sample, covering both endogenous and exogenous compounds.
  • Time Series Analysis
  • Metabotip supports dynamic analysis, allowing for the study of metabolic
    responses to various challenges—such as physical exercise, dietary changes, toxin
    exposure, or stress. It enables frequent sampling to track changes over time and
    identify individual disorders, disease predispositions and prevention strategies.
  • Enhanced Sensitivity
  • Metabotip metabolite analysis is more sensitive than blood or saliva tests due to minimal matrix effects in sweat, resulting in precise measurements with lower
    coefficients of variation.
  • Minimal Sample volume
  • Metabotip uses tiny amounts of sweat (about 100nL) for detailed analysis,
    achieving robust results even with these small sample volumes. The technique is
    sensitive enough to detect metabolites in the sub-picogram range.

Who can use it?

MetaboGnostics is working hard to make the MetaboTip technology available through
healthcare providers and practitioners in different fields as soon as possible. Healthcare professionals and practitioners looking to integrate non-invasive metabolic diagnostics into their practice will find MetaboTip an essential tool. In addition, it will be useful for anyone who would like to understand metabolic health, individuals/schools/companies/organization who are interested in ensuing the increasing health awareness.

However, this product has not yet been fully validated and has not received approval as a medical device or ‘in vitro diagnostic’. It is therefore currently intended exclusively for research purposes and is not available for use in diagnostic procedures.


Available to:
– Research Institutions
– Universities
– Pharma / Biotech companies
– R&D Laboratories
– Professional users for research purposes

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